November 20, 2024

Vininder Singh
Chief Executive Officer
BullFrog AI Holdings, Inc.
325 Ellington Blvd., Unit 317
Gaithersburg, MD 20878

       Re: BullFrog AI Holdings, Inc.
           Registration Statement on Form S-1
           Filed November 8, 2024
           File No. 333-283105
Dear Vininder Singh:

       We have conducted a limited review of your registration statement and
have the
following comment.

        Please respond to this letter by amending your registration statement
and providing
the requested information. If you do not believe the comment applies to your
facts and
circumstances or do not believe an amendment is appropriate, please tell us why
in your
response.

       After reviewing any amendment to your registration statement and the
information
you provide in response to this letter, we may have additional comments.

Registration Statement on Form S-1 Filed November 8, 2024
Management's Discussion and Analysis of Financial Condition..., page 43

1.     Please revise this section to include, in addition to the discussion of
the interim
       periods presented, a discussion of the financial condition, changes in
financial
       condition, and results of operations for the fiscal years ended December
31, 2023 and
       2022. Refer to Item 303(b) of Regulation S-K and Instruction 1 thereto.
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence
of action by the staff.
 November 20, 2024
Page 2

       Refer to Rules 460 and 461 regarding requests for acceleration. Please
allow adequate
time for us to review any amendment prior to the requested effective date of
the registration
statement.

       Please contact Jessica Dickerson at 202-551-8013 or Joe McCann at
202-551-6262
with any questions.



                                                           Sincerely,

                                                           Division of
Corporation Finance
                                                           Office of Life
Sciences
cc:   Arthur S. Marcus, Esq.