BullFrog AI Publishes Whitepaper on AI in Bioinformatics: Turning Complex Data into Actionable Insights
New publication details how BullFrog Data Networks® and bfLEAP® technology address fundamental AI challenges in drug discovery and development
GAITHERSBURG, Md., Nov. 18, 2025 (GLOBE NEWSWIRE) -- BullFrog AI Holdings, Inc. (NASDAQ: BFRG; BFRGW) ("BullFrog AI" or the "Company"), a technology-enabled drug development company using artificial intelligence (“AI”) and machine learning to enable the successful development of pharmaceuticals and biologics, today announced the publication of a new whitepaper titled “AI in Bioinformatics: Turning Complex Data into Actionable Insights with BullFrog Data Networks®.”
“The life sciences industry has reached an inflection point,” said Vin Singh, CEO of BullFrog AI. “Data abundance is no longer the issue—interpretation is. Our technology is designed to cut through the noise, delivering clarity where other AI tools struggle. This whitepaper shows exactly how we’re doing that with BullFrog Data Networks® and bfLEAP®, helping pharmaceutical partners move from data overload to data advantage. For investors, it underscores our growing leadership in the application of causal AI and bioinformatics, two of the most critical frontiers for value creation in drug development.”
Addressing the Bioinformatics Bottleneck
The whitepaper identifies three major pitfalls in modern bioinformatics: the compositional data trap, the mirage of feature importance, and the overreach of generative AI. Each contributes to the high failure rate in clinical development and the waste of billions in R&D investments annually.
BullFrog AI’s bfLEAP® platform overcomes these challenges through causal inference modeling and probabilistic validation methods originally developed at the Johns Hopkins Applied Physics Laboratory. When integrated into BullFrog Data Networks®, these capabilities enable reproducible insights across multimodal datasets—including genomics, transcriptomics, proteomics, and clinical data—creating a foundation for more reliable target identification, biomarker discovery, and patient stratification.
Positioned for Industry Transformation
The publication reinforces BullFrog AI’s expanding role in solving one of the most pressing problems in drug development: the disconnect between massive data availability and actionable biological understanding. The Company believes its modular, scalable approach—combining bfPREP™, bfLEAP®, and BullFrog Data Networks®—is well positioned to become a cornerstone of AI-enabled R&D infrastructure for global pharmaceutical and biotech organizations.
“Our whitepaper is more than an academic discussion, it’s a roadmap for how AI can finally deliver measurable impact in pharma,” Mr. Singh added. “We are demonstrating that BullFrog AI’s causal and explainable frameworks can make drug development more efficient, predictable, and ultimately, more profitable for our partners and shareholders.”
The full whitepaper is available for download here.
About BullFrog AI
BullFrog AI leverages Artificial Intelligence and machine learning to advance drug discovery and development. Through collaborations with leading research institutions, BullFrog AI uses causal AI in combination with its proprietary bfLEAP® platform to analyze complex biological data, aiming to streamline therapeutics development and reduce failure rates in clinical trials.
For more information visit BullFrog AI at: https://bullfrogai.com
Safe Harbor Statement
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Released November 18, 2025